Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.58 |
| ▸ | SQLE | Q14534 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276617 | 0.97 | KMT2A (0.70) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL2987781 | 0.97 | KMT2A (0.70) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL794095 | 0.97 | KMT2A (0.70) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL27497319 | 0.94 | KMT2A (0.67) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL12713311 | 0.92 | KMT2A (0.80) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL3092587 | 0.92 | KMT2A (0.80) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL3090339 | 0.92 | KMT2A (0.80) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL6716175 | 0.92 | KMT2A (0.80) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL10510234 | 0.92 | KMT2A (0.80) | KMT2AMEN1CYP3A4ALOX15MAPT | |
| SCHEMBL17047981 | 0.92 | KMT2A (0.80) | KMT2AMEN1CYP3A4ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669629-A | Isoflavanone compound, preparation method and application thereof | 上海交通大学医学院 | 2016-06-15 | — | — | CN | claimed |