Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.53 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829545 | 1.00 | DRD3 (0.53) | DRD3CNR2DRD2MGAT2MOGAT2 | |
| SCHEMBL28071280 | 0.85 | DRD3 (0.53) | DRD3CNR2MGAT2MOGAT2 | |
| SCHEMBL28071470 | 0.85 | DRD3 (0.53) | DRD3CNR2MGAT2MOGAT2 | |
| SCHEMBL28050491 | 0.85 | DRD3 (0.53) | DRD3CNR2 | |
| SCHEMBL28071382 | 0.85 | DRD3 (0.53) | DRD3CNR2MGAT2MOGAT2 | |
| SCHEMBL28071260 | 0.84 | DRD3 (0.52) | DRD3CNR2MGAT2MOGAT2 | |
| SCHEMBL28071290 | 0.84 | DRD3 (0.52) | DRD3CNR2MGAT2MOGAT2 | |
| SCHEMBL28071248 | 0.84 | DRD3 (0.52) | DRD3CNR2MGAT2MOGAT2 | |
| SCHEMBL28859425 | 0.82 | DRD3 (0.45) | DRD3CNR2DRD2 | |
| SCHEMBL28071300 | 0.82 | DRD3 (0.50) | DRD3CNR2MGAT2MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103596937-B | Substituted benzamide derivatives | 霍夫曼-拉罗奇有限公司 | 2016-06-29 | — | — | CN | disclosed |