Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28071493 | 1.00 | DPP4 (0.50) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL18722240 | 1.00 | DPP4 (0.50) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL28071553 | 0.98 | DPP4 (0.49) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL28071551 | 0.98 | DPP4 (0.49) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL1911508 | 0.82 | DPP4 (0.44) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL6945616 | 0.80 | DPP4 (0.43) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL14656016 | 0.79 | — | — | |
| SCHEMBL2768507 | 0.79 | DPP4 (0.44) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL1189333 | 0.79 | DPP4 (0.44) | DPP4DPP7DPP8DPP9HPGD | |
| SCHEMBL26644135 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102453001-B | Thiomorpholine compounds and its production and use | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2016-06-01 | — | — | CN | disclosed |