Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA7 | P43166 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804289 | 1.00 | HTT (0.53) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL21496861 | 0.93 | CHRNA7 (0.55) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL5083959 | 0.86 | CA12 (0.53) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL31661754 | 0.86 | CA12 (0.53) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL14261445 | 0.85 | HTT (0.73) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL9601564 | 0.85 | HTT (0.73) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL11298470 | 0.85 | HTT (0.73) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL9603015 | 0.85 | HTT (0.73) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL9603187 | 0.85 | HTT (0.73) | HTTCHRNA7CA12CA1CA2 | |
| SCHEMBL28133915 | 0.81 | CHRNA7 (0.48) | HTTCHRNA7CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |