Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.48 |
| ▸ | TUBB | P07437 | 2/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28071871 | 1.00 | EGFR (0.54) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL4330242 | 0.85 | EGFR (0.73) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL4325325 | 0.80 | EGFR (0.51) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL4325323 | 0.80 | EGFR (0.51) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL13950363 | 0.80 | EGFR (0.51) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL4318964 | 0.79 | EGFR (0.50) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL4318970 | 0.79 | EGFR (0.50) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL13950364 | 0.79 | EGFR (0.50) | EGFRKDM4EPKMTUBB1TUBB4A | |
| SCHEMBL22259980 | 0.78 | KDM4E (0.75) | EGFRKDM4EPKMMAPTHPGD | |
| SCHEMBL5618664 | 0.74 | PTP4A1 (0.70) | EGFRKDM4EPKMMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103570631-B | The preparation method of tritiated NSC 408735 | HUAZHONG AGRICULTURAL UNIVERSITY (CN) | 2016-05-25 | — | — | CN | claimed |