Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10420796 | 0.84 | TSHR (0.33) | CHRM4CHRM5CHRM1CHRM3TSHR | |
| SCHEMBL7779225 | 0.80 | DPP4 (0.43) | TSHRLMNA | |
| SCHEMBL21105595 | 0.80 | DPP4 (0.43) | TSHRLMNA | |
| SCHEMBL7779224 | 0.80 | DPP4 (0.43) | TSHRLMNA | |
| SCHEMBL1336756 | 0.80 | TSHR (0.50) | TSHRLMNAHCAR2CA12CA1 | |
| SCHEMBL1338978 | 0.80 | TSHR (0.50) | TSHRLMNAHCAR2CA12CA1 | |
| SCHEMBL8636434 | 0.80 | TSHR (0.50) | TSHRLMNAHCAR2CA12CA1 | |
| SCHEMBL571478 | 0.80 | TSHR (0.50) | TSHRLMNAHCAR2CA12CA1 | |
| SCHEMBL6680468 | 0.79 | CHRM4 (0.44) | CHRM4CHRM5CHRM1CHRM3LMNA | |
| SCHEMBL9458330 | 0.79 | CA1 (0.42) | CHRM4CHRM5CHRM1CHRM3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793266-A | Spiro-oxazolones | 豪夫迈·罗氏有限公司 | 2016-07-20 | — | — | CN | disclosed |