SCHEMBL28072138

SCHEMBL28072138

CO[Si](C)(C)OC(=O)CN

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28072192 0.83 MGAM (0.40) KDM4ELMNAMGAMGAASI
SCHEMBL9580880 0.83 KDM4E (0.32) KDM4ELMNA
SCHEMBL16540551 0.79 MGAM (0.32) KDM4ELMNAMGAMGAASI
SCHEMBL27710222 0.79 MGAM (0.32) KDM4ELMNAMGAMGAASI
SCHEMBL27999037 0.78 KDM4E (0.37) KDM4ELMNAMGAMGAASI
SCHEMBL28295961 0.77 CYP1A2 (0.33) MGAMGAASIMGAM2
SCHEMBL8405146 0.77
SCHEMBL28963326 0.76 KDM4E (0.35) KDM4ELMNAMGAMGAASI
SCHEMBL28036496 0.76 KDM4E (0.35) KDM4ELMNAMGAMGAASI
SCHEMBL28120226 0.75 KDM4E (0.33) KDM4ELMNAMGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793325-A Silicate resins and methods of preparing same 道康宁公司 2016-07-20 CN disclosed