Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1958254 | 0.90 | BCL2 (0.71) | BCL2BCL2L1 | |
| SCHEMBL2996436 | 0.85 | BCL2 (0.74) | BCL2BCL2L1 | |
| SCHEMBL1742388 | 0.84 | BCL2 (0.65) | BCL2BCL2L1 | |
| SCHEMBL28072124 | 0.84 | BCL2 (0.68) | BCL2BCL2L1 | |
| SCHEMBL1958426 | 0.83 | BCL2 (0.73) | BCL2BCL2L1 | |
| SCHEMBL1955301 | 0.83 | BCL2 (0.62) | BCL2BCL2L1 | |
| SCHEMBL1744765 | 0.82 | BCL2 (0.69) | BCL2BCL2L1 | |
| SCHEMBL1956361 | 0.82 | BCL2 (0.57) | BCL2BCL2L1 | |
| SCHEMBL1956951 | 0.81 | BCL2 (0.61) | BCL2BCL2L1 | |
| SCHEMBL1742180 | 0.81 | BCL2 (0.63) | BCL2BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102307872-B | BCL-2-selectively apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2016-06-15 | — | — | CN | disclosed |