Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173281 | 0.95 | HTT (0.68) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL14173280 | 0.95 | HTT (0.68) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13220831 | 0.90 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL16982216 | 0.90 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL13289974 | 0.90 | HTT (0.76) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL14173271 | 0.90 | POLB (0.61) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL11053172 | 0.90 | POLB (0.61) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL12918799 | 0.89 | HTT (0.74) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL11168834 | 0.89 | HTT (0.74) | HTTPOLBAPEX1TDP1TSHR | |
| SCHEMBL11172057 | 0.89 | HTT (0.74) | HTTPOLBAPEX1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829922-B | Polymer composition and the method for manufacturing ophthalmic lens using the polymer composition | 依视路国际公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105829922-A | Polymer Composition And Methods Using Said Polymer Composition To Manufacture Ophthalmic Lens | 埃西勒国际通用光学公司 | 2016-08-03 | — | — | CN | disclosed |