Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 18/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.52 |
| ▸ | ADCK1 | Q86TW2 | 1/20 | 0.52 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345623 | 0.81 | MAP2K1 (0.52) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL389984 | 0.81 | MAP2K1 (0.62) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL935637 | 0.79 | MAP2K1 (0.50) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL2954977 | 0.79 | MAP2K1 (0.69) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL10285170 | 0.78 | MAP2K1 (0.49) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL12943976 | 0.78 | MAP2K1 (0.56) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL685422 | 0.77 | MAP2K1 (0.61) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL346016 | 0.76 | MAP2K1 (0.49) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL1681367 | 0.76 | MAP2K1 (0.50) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 | |
| SCHEMBL12869983 | 0.75 | MAP2K1 (0.61) | MAP2K1MAP2K2CHEK1MAPK10PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103479604-B | N-(virtue amino) sulfamide derivative including polymorph and compositions, its using method and preparation method as mek inhibitor | 阿迪生物科学公司 | 2016-08-10 | — | — | CN | disclosed |