Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.85 |
| ▸ | PPARD | Q03181 | 6/20 | 0.85 |
| ▸ | PPARA | Q07869 | 6/20 | 0.85 |
| ▸ | F7 | P08709 | 6/20 | 0.85 |
| ▸ | F3 | P13726 | 6/20 | 0.85 |
| ▸ | TERT | O14746 | 3/20 | 0.85 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.85 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.85 |
| ▸ | FABP4 | P15090 | 3/20 | 0.85 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.85 |
| ▸ | MAPT | P10636 | 2/20 | 0.85 |
| ▸ | BLM | P54132 | 2/20 | 0.85 |
| ▸ | LMNA | P02545 | 2/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.85 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.85 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.85 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.85 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.85 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.85 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL31330278 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Nervonic Acid SCHEMBL27652694 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28106476 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL3751821 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Erucic Acid SCHEMBL6561087 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL27816432 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL27890987 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL29601875 | 0.96 | PPARG (0.92) | PPARGPPARDPPARAF7F3 | |
| Linoleic Acid SCHEMBL28754753 | 0.95 | PPARG (0.93) | PPARGPPARDPPARAF7F3 | |
| Linoleic Acid SCHEMBL27343411 | 0.95 | PPARG (0.93) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467991-A | A kind of fireproof coating for distribution box | 江苏海德环境科技有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-107892891-A | A kind of conductive pressure sensitive adhesive for electro-medical pole piece and preparation method thereof | 南京诺邦新材料有限公司 | 2018-04-10 | — | — | CN | claimed |
| CN-104164283-B | Micro emulsion metalworking fluid | 清华大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-106117678-A | A kind of anti-aging rubber | 山东永泰集团有限公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-105968814-A | Fire-resistant rubber | 山东永泰集团有限公司 | 2016-09-28 | — | — | CN | disclosed |