SCHEMBL2807332

SCHEMBL2807332

O=C(O)/C=C/CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900335 1.00
SCHEMBL491480 1.00
SCHEMBL6913553 0.97
SCHEMBL6915369 0.97
SCHEMBL6915268 0.97
SCHEMBL6916943 0.97
SCHEMBL6917318 0.97
SCHEMBL6917129 0.97
SCHEMBL6916375 0.97
SCHEMBL8997145 0.78 TDP1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843473-A Preparation method of levocarnitine impurity 常州寅盛药业有限公司 2024-04-09 CN claimed
US-9745341-B2 Tubulysins and processes for preparing ENDOCYTE, INC. (US) 2017-08-29 US claimed
US-20160108085-A1 TUBULYSINS AND PROCESSES FOR PREPARING ENDOCYTE INC (US) 2016-04-21 US claimed
US-9073884-B2 Anti-inflammatory and quorum sensing inhibition compounds and methods of making and using them THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-07-07 US claimed
EP-1789029-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION Interstitial Therapeutics (CH) 2007-05-30 EP claimed
WO-2006024489-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024490-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024491-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
EP-3746436-B1 FUSED RING COMPOUNDS HOFFMANN LA ROCHE (CH) 2026-05-20 EP disclosed
WO-2025092986-A1 POLYCYCLIC COMPOUND, PREPARATION METHODS AND MEDICINAL USES THEREOF JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) 2025-05-08 WO disclosed
US-20250059163-A1 FUSED RING COMPOUNDS GENENTECH INC (US) 2025-02-20 US disclosed
EP-4501932-A2 KRAS G12C INHIBITORS Mirati Therapeutics, Inc. (US) 2025-02-05 EP disclosed
EP-4483881-A2 FUSED RING COMPOUNDS F. Hoffmann-La Roche AG (CH) 2025-01-01 EP disclosed
US-20240417408-A1 SMALL MOLECULE INHIBITORS OF KRAS G12C MUTANT TAIHO PHARMACEUTICAL CO., LTD. (JP) 2024-12-19 US disclosed
WO-1997036903-A1 PYRROLOPYRROLONE DERIVATIVES AS INHIBITORS OF NEUTROPHIL ELASTASE GLAXO GROUP LIMITED (GB) 1997-10-09 WO disclosed
US-5656756-A PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY, ANTITUMOR AGENTS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1997-08-12 US disclosed
WO-1995029914-A1 A METHOD OF SYNTHESIZING 5,15-DIARYLBENZOCHLORIN-7-ONE COMPOUNDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 1995-11-09 WO disclosed
US-4731391-A Process of making a superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-03-15 US disclosed
US-4725629-A Process of making an interpenetrating superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 US disclosed
US-4725628-A Process of making a crosslinked superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 US disclosed