Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.40 |
| ▸ | SCN1A | P35498 | 2/20 | 0.39 |
| ▸ | SCN2B | O60939 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16094574 | 0.86 | SCN9A (0.41) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL16094579 | 0.85 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL17509683 | 0.85 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL17961886 | 0.84 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL17509681 | 0.84 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL16120744 | 0.84 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL17523542 | 0.84 | SCN9A (0.39) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL16094667 | 0.82 | SCN9A (0.40) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL16094614 | 0.81 | SCN9A (0.39) | SCN9ASCN5ACYP2C9CYP3A4SCN8A | |
| SCHEMBL16094619 | 0.81 | SCN9A (0.39) | SCN9ASCN5ACYP2C9CYP3A4SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105611923-A | Sodium channel modulators for the treatment of pain and diabetes | CHROMOCELL CORP | 2016-05-25 | — | — | CN | disclosed |