Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 17/20 | 0.73 |
| ▸ | MAP3K20 | Q9NYL2 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075306 | 0.90 | BRAF (0.72) | BRAFMAP3K20CYP3A4 | |
| SCHEMBL28074720 | 0.88 | BRAF (0.72) | BRAFMAP3K20CYP3A4 | |
| SCHEMBL28074745 | 0.80 | BRAF (0.58) | BRAFMAP3K20 | |
| SCHEMBL28074727 | 0.80 | BRAF (0.56) | BRAFMAP3K20CYP3A4 | |
| SCHEMBL21047210 | 0.78 | BRAF (1.00) | BRAFMAP3K20 | |
| SCHEMBL28075261 | 0.78 | BRAF (0.76) | BRAFMAP3K20 | |
| SCHEMBL21046873 | 0.77 | BRAF (0.72) | BRAFMAP3K20 | |
| SCHEMBL21046769 | 0.77 | BRAF (0.77) | BRAFMAP3K20 | |
| SCHEMBL28074722 | 0.77 | BRAF (1.00) | BRAFMAP3K20 | |
| SCHEMBL21046838 | 0.76 | BRAF (0.70) | BRAFMAP3K20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732614-B | Sulfoamido aryl acetylene compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2018-06-12 | — | — | CN | disclosed |
| CN-105732614-A | Sulfonamide aryl acetylene compound and use thereof | 中国科学院广州生物医药与健康研究院 | 2016-07-06 | — | — | CN | disclosed |