Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21046714 | 0.92 | BRAF (0.85) | BRAFMAP3K20 | |
| SCHEMBL21047158 | 0.92 | BRAF (1.00) | BRAFMAP3K20 | |
| SCHEMBL21046746 | 0.92 | BRAF (0.85) | BRAFMAP3K20 | |
| SCHEMBL21046946 | 0.92 | BRAF (0.85) | BRAFMAP3K20 | |
| SCHEMBL21046876 | 0.91 | BRAF (0.82) | BRAFMAP3K20 | |
| SCHEMBL21046722 | 0.90 | BRAF (0.81) | BRAFMAP3K20 | |
| SCHEMBL21046779 | 0.89 | BRAF (0.81) | BRAFMAP3K20 | |
| SCHEMBL21046833 | 0.89 | BRAF (0.81) | BRAFMAP3K20 | |
| SCHEMBL21048164 | 0.89 | MAP3K20 (0.81) | BRAFMAP3K20 | |
| SCHEMBL21046937 | 0.89 | BRAF (0.81) | BRAFMAP3K20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732614-B | Sulfoamido aryl acetylene compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2018-06-12 | — | — | CN | disclosed |
| CN-105732614-A | Sulfonamide aryl acetylene compound and use thereof | 中国科学院广州生物医药与健康研究院 | 2016-07-06 | — | — | CN | disclosed |