Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K20 | Q9NYL2 | 11/20 | 0.78 |
| ▸ | BRAF | P15056 | 12/20 | 0.77 |
| ▸ | KIT | P10721 | 1/20 | 0.70 |
| ▸ | FRK | P42685 | 1/20 | 0.70 |
| ▸ | SIK1 | P57059 | 1/20 | 0.70 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.70 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.70 |
| ▸ | SRMS | Q9H3Y6 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074866 | 0.94 | MAP3K20 (0.77) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28075289 | 0.91 | MAP3K20 (0.86) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074726 | 0.89 | BRAF (0.84) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074717 | 0.88 | MAP3K20 (0.86) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074832 | 0.87 | MAP3K20 (1.00) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074826 | 0.87 | MAP3K20 (0.81) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074719 | 0.86 | BRAF (0.76) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074813 | 0.84 | BRAF (0.79) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28074722 | 0.84 | BRAF (1.00) | MAP3K20BRAFKITFRKSIK1 | |
| SCHEMBL28830158 | 0.83 | BRAF (0.73) | MAP3K20BRAFKITFRKSIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732614-B | Sulfoamido aryl acetylene compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2018-06-12 | — | — | CN | disclosed |
| CN-105732614-A | Sulfonamide aryl acetylene compound and use thereof | 中国科学院广州生物医药与健康研究院 | 2016-07-06 | — | — | CN | disclosed |