Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5910853 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL28093187 | 0.86 | — | — | |
| Iodide SCHEMBL27895039 | 0.86 | — | — | |
| SCHEMBL27984701 | 0.76 | TDP1 (0.45) | TDP1ALDH1A1KDM4EMEN1MITF | |
| SCHEMBL570666 | 0.76 | — | — | |
| SCHEMBL4671406 | 0.76 | TDP1 (0.47) | TDP1ALDH1A1EGLN3KDM4EMEN1 | |
| Acetic Acid SCHEMBL27855127 | 0.75 | TDP1 (0.44) | TDP1ALDH1A1EGLN3KDM4ETBXAS1 | |
| Hydrochloric Acid SCHEMBL4674923 | 0.75 | TDP1 (0.46) | TDP1ALDH1A1EGLN3TBXAS1CYP3A4 | |
| SCHEMBL27735298 | 0.75 | TDP1 (0.46) | TDP1ALDH1A1EGLN3MAPTTBXAS1 | |
| Ammonia Solution, Strong SCHEMBL27843547 | 0.75 | TDP1 (0.46) | TDP1ALDH1A1EGLN3MAPTTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103430096-B | Original edition of lithographic printing plate, its method for platemaking and polyvalent isocyanate compound | 富士胶片株式会社 | 2016-06-22 | — | — | CN | disclosed |