Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 11/20 | 0.60 |
| ▸ | PPIB | P23284 | 9/20 | 0.56 |
| ▸ | PPIG | Q13427 | 7/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14644444 | 1.00 | PPID (0.60) | PPIDPPIBPPIGEPHX1PPIA | |
| SCHEMBL15834711 | 0.82 | PPID (0.43) | PPIDPPIBPPIG | |
| SCHEMBL2033333 | 0.78 | PPID (0.61) | PPIDPPIBPPIGHRH3 | |
| SCHEMBL2042048 | 0.77 | PPID (0.66) | PPIDPPIBPPIGHRH3 | |
| SCHEMBL2038192 | 0.77 | PPID (0.70) | PPIDPPIBPPIGEPHX1PPIA | |
| SCHEMBL2036090 | 0.77 | PPID (0.63) | PPIDPPIBPPIGEPHX1 | |
| SCHEMBL12643948 | 0.75 | PPID (0.65) | PPIDPPIBPPIGEPHX1PPIA | |
| SCHEMBL2039594 | 0.75 | PPID (0.65) | PPIDPPIBPPIGEPHX1PPIA | |
| SCHEMBL2039591 | 0.75 | PPID (0.65) | PPIDPPIBPPIGEPHX1PPIA | |
| SCHEMBL19882177 | 0.74 | PPID (0.55) | PPIDPPIBPPIGEPHX1PPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693597-A | New inhibitors of cyclophilins and uses thereof | 国家健康与医学研究院（INSERM） | 2016-06-22 | — | — | CN | disclosed |