SCHEMBL28075705

SCHEMBL28075705

Cc1c(N)cc(C(=O)O)c(C(=O)ON)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.49
KMT2A Q03164 4/20 0.49
MEN1 O00255 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
ALDH1A1 P00352 3/20 0.36
CDC25B P30305 1/20 0.36
CASP6 P55212 1/20 0.36
RCE1 Q9Y256 1/20 0.36
GFER P55789 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
GABRP O00591 2/20 0.35
GABRD O14764 2/20 0.35
GABRA1 P14867 2/20 0.35
GABRB1 P18505 2/20 0.35
GABRG2 P18507 2/20 0.35
GABRB3 P28472 2/20 0.35
GABRA5 P31644 2/20 0.35
GABRA3 P34903 2/20 0.35
GABRA2 P47869 2/20 0.35
GABRB2 P47870 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5056042 0.83 KDM4E (0.57) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL28075649 0.76 TSHR (0.45) TDP1ALDH1A1CASP6MAPTPOLB
SCHEMBL1260739 0.75 KDM4E (0.67) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL1271992 0.72 KDM4E (0.62) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL17774727 0.72 KDM4E (0.57) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL4655479 0.72 KDM4E (0.57) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL8016297 0.71 KDM4E (0.50) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL19149297 0.71 KDM4E (0.55) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL28198037 0.71 KDM4E (0.55) KDM4EKMT2AMEN1TDP1ALDH1A1
SCHEMBL28679886 0.70 KDM4E (0.64) KDM4EKMT2AMEN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105622548-A High-temperature-resistant glycidyl amine type multifunctional epoxy resin and preparation method thereof UNIV HEFEI TECHNOLOGY 2016-06-01 CN disclosed