Benzene

Benzene

SCHEMBL28075751

COC(=O)CO.c1ccccc1.c1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
HSD17B10 Q99714 2/20 0.46
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
POLB P06746 1/20 0.43
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 2/20 0.42
KMT2A Q03164 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
HSP90AB1 P08238 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
AKT1 P31749 1/20 0.37
TET2 Q6N021 1/20 0.37
MEN1 O00255 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28412102 0.91 TSHR (0.59) TSHRHSD17B10MGAMGAASI
SCHEMBL21453 0.91
Acetic Acid SCHEMBL27369424 0.88 MGAM (0.52) TSHRHSD17B10MGAMGAASI
Glycolic Acid SCHEMBL28382388 0.88 TSHR (0.50) TSHRHSD17B10MGAMGAASI
SCHEMBL29164276 0.88
Methoxymethane SCHEMBL27633144 0.88
SCHEMBL28257383 0.88
SCHEMBL29064737 0.88
Ammonia Solution, Strong SCHEMBL27533041 0.88
Methyl Alcohol SCHEMBL27781011 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102964345-B A kind of preparation method of 2-hydroxyl-2,2-diphenyl acetic acid-3 α-(8-azabicyclo [3,2,1])-3-monooctyl ester 四川理工学院 2016-07-13 CN claimed
CN-102964345-B A kind of preparation method of 2-hydroxyl-2,2-diphenyl acetic acid-3 α-(8-azabicyclo [3,2,1])-3-monooctyl ester 四川理工学院 2016-07-13 CN disclosed
CN-102964345-B A kind of preparation method of 2-hydroxyl-2,2-diphenyl acetic acid-3 α-(8-azabicyclo [3,2,1])-3-monooctyl ester 四川理工学院 2016-07-13 CN disclosed