Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707225 | 0.92 | KDM4E (0.52) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL15283932 | 0.92 | KDM4E (0.52) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL18000525 | 0.91 | KDM4E (0.54) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL29788812 | 0.91 | KDM4E (0.54) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL28075713 | 0.88 | MAPT (0.47) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL30094302 | 0.78 | KDM4E (0.52) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL16618621 | 0.78 | KDM4E (0.52) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL19165991 | 0.76 | TOP1 (0.50) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL26833473 | 0.76 | CCR1 (0.39) | KDM4ELMNAMAPTHTTTDP1 | |
| SCHEMBL16484527 | 0.76 | BRD4 (0.48) | KDM4ELMNAMAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669544-B | A kind of brominated hole mobile material and preparation method thereof | 电子科技大学 | 2017-11-17 | — | — | CN | disclosed |
| CN-105669544-A | Bromine-containing hole-transporting material and preparation method thereof | 电子科技大学 | 2016-06-15 | — | — | CN | disclosed |