Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198986 | 0.87 | EGFR (0.46) | EGFRKDM4EMEN1KMT2ANPC1 | |
| SCHEMBL14867541 | 0.87 | KDM4E (0.52) | KDM4EMEN1KMT2AMMP9HDAC6 | |
| SCHEMBL15901697 | 0.86 | KDM4E (0.51) | KDM4EMEN1KMT2AMMP9HDAC6 | |
| SCHEMBL29109182 | 0.79 | BRD4 (0.52) | KDM4EMEN1KMT2AMMP9GMNN | |
| SCHEMBL30663469 | 0.79 | BRD4 (0.52) | KDM4EMEN1KMT2AMMP9GMNN | |
| SCHEMBL29788812 | 0.79 | KDM4E (0.54) | KDM4EMEN1KMT2AMMP9GMNN | |
| SCHEMBL18000525 | 0.79 | KDM4E (0.54) | KDM4EMEN1KMT2AMMP9GMNN | |
| SCHEMBL4362401 | 0.78 | EGFR (0.53) | EGFRFBP1ABCG2KDR | |
| SCHEMBL15900117 | 0.77 | FABP1 (0.52) | KDM4EMEN1KMT2AMMP9PKM | |
| SCHEMBL4900112 | 0.73 | MAPK10 (0.37) | KDM4EMEN1KMT2AMMP9HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669544-A | Bromine-containing hole-transporting material and preparation method thereof | 电子科技大学 | 2016-06-15 | — | — | CN | disclosed |