Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL2503939 | 0.97 | TDP1 (0.36) | FFAR3LCKFYNTDP1TET2 | |
| Acetic Acid SCHEMBL28062474 | 0.86 | FFAR3 (0.50) | FFAR3LCKFYNTP53 | |
| Methacrylic Acid SCHEMBL28486169 | 0.85 | TDP1 (0.32) | TDP1 | |
| Methacrylic Acid SCHEMBL28776693 | 0.80 | TDP1 (0.44) | FFAR3LCKFYNTDP1TET2 | |
| Methacrylic Acid SCHEMBL1238167 | 0.80 | FFAR3 (0.58) | FFAR3LCKFYNTDP1TET2 | |
| Methacrylic Acid SCHEMBL8426536 | 0.80 | FFAR3 (0.58) | FFAR3LCKFYNTDP1TET2 | |
| Methacrylic Acid SCHEMBL28106790 | 0.80 | FFAR3 (0.58) | FFAR3LCKFYNTDP1TET2 | |
| Methacrylic Acid SCHEMBL27560581 | 0.79 | TDP1 (0.35) | FFAR3LCKFYNTDP1ALDH1A1 | |
| Methacrylic Acid SCHEMBL538064 | 0.77 | TP53 (0.44) | FFAR3LCKFYNTDP1TET2 | |
| Methacrylic Acid SCHEMBL3642988 | 0.77 | TP53 (0.44) | FFAR3LCKFYNTDP1TET2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103732384-B | For manufacturing the mixing method of eyeglass, device and composite part | 镜片公司 | 2016-07-13 | — | — | CN | disclosed |