Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472457 | 0.86 | HTR2C (0.46) | HTR2CDAORNASEH1KDM4EALDH1A1 | |
| SCHEMBL27886361 | 0.84 | GAA (0.53) | CHRM4CHRM5CHRM1CHRM3HTR2A | |
| SCHEMBL1262849 | 0.83 | AOC3 (0.47) | CHRM4CHRM5CHRM1CHRM3HTR2A | |
| SCHEMBL30327261 | 0.83 | HTR2C (0.43) | CHRM4CHRM5CHRM1CHRM3HTR2A | |
| SCHEMBL16463218 | 0.81 | GAA (0.42) | CHRM4CHRM5CHRM1CHRM3HTR2A | |
| SCHEMBL16465453 | 0.80 | CHRM4 (0.40) | CHRM4CHRM5CHRM1CHRM3HTR2A | |
| SCHEMBL629988 | 0.76 | PDE4A (0.52) | CHRM4CHRM5CHRM1CHRM3HTR2A | |
| SCHEMBL11267581 | 0.76 | ATM (0.48) | TP53 | |
| SCHEMBL16463217 | 0.75 | GAA (0.49) | HTR6GAAPKMTSHRAOC3 | |
| SCHEMBL4329849 | 0.74 | HTR2C (0.43) | CHRM4CHRM5CHRM1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105748500-A | Rhizoma gastrodiae effective constituent composition for preventing and curing dementia and application of composition | 中国科学院大连化学物理研究所 | 2016-07-13 | — | — | CN | claimed |
| CN-105748500-A | Rhizoma gastrodiae effective constituent composition for preventing and curing dementia and application of composition | 中国科学院大连化学物理研究所 | 2016-07-13 | — | — | CN | disclosed |