Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736111 | 0.98 | TP53 (0.38) | TP53TSHRCHRM1AKR1A1CHRM3 | |
| SCHEMBL2368442 | 0.96 | TP53 (0.36) | TP53TSHRCHRM1AKR1A1CHRM3 | |
| SCHEMBL6735043 | 0.85 | TP53 (0.44) | TP53TSHR | |
| Ammonia Solution, Strong SCHEMBL27619137 | 0.84 | TP53 (0.48) | TP53 | |
| SCHEMBL28708788 | 0.82 | TP53 (0.33) | TP53 | |
| SCHEMBL10867424 | 0.82 | TP53 (0.50) | TP53 | |
| SCHEMBL27956716 | 0.82 | TP53 (0.50) | TP53 | |
| SCHEMBL3501851 | 0.80 | TP53 (0.33) | TP53 | |
| SCHEMBL14779447 | 0.77 | TP53 (0.39) | TP53TSHRCHRM1AKR1A1CHRM3 | |
| SCHEMBL2368437 | 0.74 | CYP3A4 (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104250380-B | Dendritic polymer, dendritic polymer monomer, and preparation methods and application of two | 中国石油化工股份有限公司 | 2017-02-01 | — | — | CN | disclosed |
| CN-104250358-B | A kind of hyper branched copolymer and its preparation method and application | 中国石油化工股份有限公司 | 2016-08-17 | — | — | CN | disclosed |