Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21245566 | 0.88 | DDB1 (0.43) | DDB1CRBNTRPC6ALOX5APFEN1 | |
| SCHEMBL30620837 | 0.86 | ALOX5AP (0.46) | ALOX5APFEN1UCHL1NPC1 | |
| SCHEMBL30476145 | 0.85 | ALOX5AP (0.43) | DDB1CRBNALOX5APFEN1UCHL1 | |
| SCHEMBL28958074 | 0.85 | NR1H2 (0.43) | DDB1CRBNLCKJAK3BTK | |
| SCHEMBL29497122 | 0.82 | DDB1 (0.60) | DDB1CRBNTRPC6ALOX5APFEN1 | |
| SCHEMBL611718 | 0.82 | DDB1 (0.60) | DDB1CRBNTRPC6ALOX5APFEN1 | |
| SCHEMBL30519935 | 0.81 | PDE4B (0.53) | DDB1CRBNTRPC6ALOX5APFEN1 | |
| SCHEMBL29743593 | 0.81 | PDE4B (0.53) | DDB1CRBNTRPC6ALOX5APFEN1 | |
| SCHEMBL608688 | 0.81 | PDE4B (0.53) | DDB1CRBNTRPC6ALOX5APFEN1 | |
| SCHEMBL609655 | 0.81 | PDE4B (0.53) | DDB1CRBNTRPC6ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658646-A | Aminoheteroaryl benzamides as kinase inhibitors | 诺华股份有限公司 | 2016-06-08 | — | — | CN | disclosed |