SCHEMBL28076826

SCHEMBL28076826

CCCCCCCC(P)CC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
CA1 P00915 1/20 0.39
MAPT P10636 1/20 0.38
LCK P06239 1/20 0.38
PPARD Q03181 1/20 0.38
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27932249 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27931965 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27948100 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27932029 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27932134 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27932123 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27948114 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27932036 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27932125 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL27947980 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105754099-B Composition and polymer 旭化成株式会社 2018-09-18 CN disclosed
CN-103502315-B Composition and polymer 旭化成株式会社 2016-08-17 CN disclosed
CN-105754099-A Composition and polymer 旭化成株式会社 2016-07-13 CN disclosed