Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660552 | 0.81 | KIT (0.41) | PIM1PIM3PIM2KITMET | |
| SCHEMBL13156334 | 0.78 | HIF1A (0.44) | HIF1AEPAS1MAOBHTR2A | |
| SCHEMBL15599255 | 0.76 | PARP1 (0.37) | PIM1PIM3PIM2HIF1AEPAS1 | |
| SCHEMBL11358788 | 0.74 | CNR2 (0.38) | HIF1AEPAS1MAOB | |
| SCHEMBL18053881 | 0.72 | MAPT (0.41) | PIM1PIM3PIM2 | |
| SCHEMBL30781068 | 0.72 | MAPT (0.41) | PIM1PIM3PIM2 | |
| SCHEMBL30523622 | 0.71 | MAOB (0.35) | PIM1PIM3PIM2HIF1AEPAS1 | |
| SCHEMBL660359 | 0.71 | CYP11B1 (0.52) | CYP2A6CTSDBACE1 | |
| SCHEMBL8959298 | 0.70 | AKR1B1 (0.43) | HIF1A | |
| SCHEMBL12180466 | 0.70 | KDM4E (0.38) | PIM1PIM3PIM2KITMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965147-B | Benzofuran derivatives | 武田药品工业株式会社 | 2016-08-24 | — | — | CN | disclosed |