Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17407740 | 0.88 | KMT2A (0.43) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| SCHEMBL13223118 | 0.83 | KMT2A (0.66) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| SCHEMBL26457583 | 0.81 | ADORA2A (0.49) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| SCHEMBL13702955 | 0.81 | ADORA1 (0.49) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| SCHEMBL9379954 | 0.76 | CYP1A2 (0.58) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| SCHEMBL7505266 | 0.76 | KMT2A (0.58) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| SCHEMBL13702954 | 0.75 | ADORA1 (0.44) | KMT2AKDM4EALDH1A1MEN1RAB9A | |
| SCHEMBL22461072 | 0.74 | CYP1A2 (0.34) | KMT2ACYP1A2XIAP | |
| SCHEMBL25317234 | 0.73 | KDM4E (0.39) | KMT2ACYP1A2XIAPPOLBKDM4E | |
| Hydrochloric Acid SCHEMBL11568338 | 0.73 | KMT2A (0.54) | KMT2ACYP1A2XIAPPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646487-A | Bromo-1,8-naphthyridine derivatives of class and preparation method of bromo-1,8-naphthyridine derivatives of class | 红河学院 | 2016-06-08 | — | — | CN | disclosed |