Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.75 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391800 | 0.86 | DPP4 (1.00) | DPP4OPRM1OPRK1 | |
| SCHEMBL23712233 | 0.86 | DPP4 (1.00) | DPP4OPRM1OPRK1 | |
| Alogliptin SCHEMBL17036596 | 0.83 | DPP4 (1.00) | DPP4OPRM1OPRK1 | |
| Alogliptin SCHEMBL121028 | 0.83 | DPP4 (1.00) | DPP4OPRM1OPRK1 | |
| Alogliptin SCHEMBL29352995 | 0.83 | DPP4 (1.00) | DPP4OPRM1OPRK1 | |
| Alogliptin SCHEMBL174188 | 0.83 | DPP4 (1.00) | DPP4OPRM1OPRK1 | |
| SCHEMBL7932462 | 0.83 | DPP4 (0.77) | DPP4OPRM1OPRK1ALDH1A1 | |
| Alogliptin SCHEMBL475872 | 0.82 | DPP4 (0.98) | DPP4OPRM1OPRK1 | |
| Alogliptin SCHEMBL17781892 | 0.82 | DPP4 (0.98) | DPP4OPRM1OPRK1 | |
| SCHEMBL28406504 | 0.81 | DPP4 (0.91) | DPP4OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646446-A | An alogliptin purifying method | 海正辉瑞制药有限公司 | 2016-06-08 | — | — | CN | disclosed |