Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17747330 | 1.00 | HTR2C (0.49) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL16398156 | 0.98 | HTR2C (0.47) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL28078255 | 0.98 | HTR2C (0.47) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL18312709 | 0.95 | HTR2C (0.50) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL1050248 | 0.95 | HTR2C (0.50) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL16398448 | 0.88 | HTR2C (0.53) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL17747344 | 0.88 | HTR2C (0.53) | HTR2CMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL7545433 | 0.77 | HTR2C (0.70) | HTR2CMEN1KMT2ADRD2MCOLN2 | |
| SCHEMBL30938438 | 0.75 | HTR2C (0.68) | HTR2CMEN1KMT2ADRD2MCOLN2 | |
| SCHEMBL6695552 | 0.75 | HTR2C (0.68) | HTR2CMEN1KMT2ADRD2MCOLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658656-A | 1, 1' -spiroindane-7, 7-bisphosphine oxides as highly active supporting ligands in palladium-catalyzed asymmetric Heck reactions | 南洋理工大学 | 2016-06-08 | — | — | CN | disclosed |