Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.43 |
| ▸ | HTR2B | P41595 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28101025 | 0.88 | HTR2C (0.46) | SLC6A4DDR1HTR2CHTR2BHTR6 | |
| SCHEMBL5372606 | 0.85 | HTR2C (0.55) | SLC6A4HTR2CHTR2BHTR6HTR1A | |
| Hydrochloric Acid SCHEMBL10276355 | 0.84 | HTR2C (0.54) | SLC6A4HTR2CHTR2BHTR6HTR1A | |
| SCHEMBL13034355 | 0.81 | SLC6A4 (0.52) | SLC6A4DDR1HTR2CHTR2BHTR6 | |
| Tert-Butyl Formate SCHEMBL28078907 | 0.81 | HRH1 (0.43) | SLC6A4HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3106060 | 0.80 | SLC6A4 (0.51) | SLC6A4DDR1HTR2CHTR2BHTR6 | |
| SCHEMBL16657594 | 0.76 | SLC6A4 (0.56) | SLC6A4DDR1HTR2CHTR2BHTR6 | |
| SCHEMBL12263512 | 0.76 | HPGD (0.49) | SLC6A4HTR2CHTR2B | |
| Tert-Butyl Formate SCHEMBL27805796 | 0.76 | UTS2R (0.43) | SLC6A4HTR2CHTR2BHTR1ASLC6A2 | |
| Tert-Butyl Formate SCHEMBL28328551 | 0.75 | HRH1 (0.48) | SLC6A4HTR2CHTR2BHTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-A | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2016-07-20 | — | — | CN | disclosed |