Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | BCL9 | O00512 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28078864 | 1.00 | SCN9A (0.40) | SCN9ACNR2BCL9CTNNB1IRAK4 | |
| SCHEMBL17061892 | 0.93 | SCN9A (0.44) | SCN9ACNR2BCL9CTNNB1IRAK4 | |
| SCHEMBL16759432 | 0.93 | SCN9A (0.44) | SCN9ACNR2BCL9CTNNB1IRAK4 | |
| Tert-Butyl Formate SCHEMBL28831462 | 0.86 | SCN9A (0.49) | SCN9A | |
| Tert-Butyl Formate SCHEMBL28831463 | 0.86 | SCN9A (0.49) | SCN9A | |
| Tert-Butyl Formate SCHEMBL28950756 | 0.86 | SCN9A (0.49) | SCN9A | |
| SCHEMBL17061927 | 0.82 | SCN9A (0.48) | SCN9A | |
| SCHEMBL16758889 | 0.82 | SCN9A (0.48) | SCN9A | |
| Tert-Butyl Formate SCHEMBL28078729 | 0.80 | SCN9A (0.45) | SCN9A | |
| Tert-Butyl Formate SCHEMBL28078800 | 0.80 | SCN9A (0.47) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793238-A | Substituted benzamides and methods of use thereof | 基因泰克公司 | 2016-07-20 | — | — | CN | disclosed |