Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PARP6 | Q2NL67 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.46 |
| ▸ | PARP8 | Q8N3A8 | 1/20 | 0.46 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.46 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.46 |
| ▸ | PRAP1 | Q96NZ9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28316956 | 0.99 | PARP1 (0.55) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28876141 | 0.97 | PARP1 (0.57) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28315540 | 0.89 | PARP1 (0.56) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28315536 | 0.88 | PARP1 (0.53) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28316946 | 0.87 | PARP1 (0.51) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL15846924 | 0.87 | PARP1 (0.56) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28316958 | 0.87 | PARP1 (0.51) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28316128 | 0.85 | PARP1 (0.51) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28315479 | 0.85 | PARP1 (0.50) | PARP1PARP2TNKSADORA1CDK6 | |
| SCHEMBL28316400 | 0.84 | PARP1 (0.56) | PARP1PARP2TNKSADORA1CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793248-B | Phthalazinone derivatives and process for preparing the same | 日东制药株式会社 | 2019-08-16 | — | — | CN | claimed |
| CN-105793248-B | Phthalazinone derivatives and process for preparing the same | 日东制药株式会社 | 2019-08-16 | — | — | CN | disclosed |
| CN-105793248-A | Novel phthalazinone derivatives and process for preparing the same | 日东制药株式会社 | 2016-07-20 | — | — | CN | disclosed |