Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29458668 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL28898058 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL499457 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL499761 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL499942 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL28448853 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL11785301 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL499571 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL8101073 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 | |
| SCHEMBL28898618 | 0.98 | TSHR (0.49) | TSHRFAAHACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102333840-B | Treatment fluids comprising relative permeability modifiers and methods of use | 哈利伯顿能源服务公司 | 2016-08-31 | — | — | CN | disclosed |