Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 10/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.37 |
| ▸ | IDH1 | O75874 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15350461 | 0.99 | SCN9A (0.42) | SCN9AMAPK1AAK1IDH1 | |
| SCHEMBL17244897 | 0.89 | SCN9A (0.42) | SCN9AMAPK1AAK1IDH1 | |
| SCHEMBL16045149 | 0.87 | IDH1 (0.43) | SCN9AAAK1IDH1 | |
| SCHEMBL4550317 | 0.87 | IDH1 (0.43) | SCN9AAAK1IDH1 | |
| Hydrochloric Acid SCHEMBL2714340 | 0.86 | IDH1 (0.43) | SCN9AAAK1IDH1 | |
| SCHEMBL10291359 | 0.85 | MAPK1 (0.42) | SCN9AMAPK1AAK1 | |
| Hydrochloric Acid SCHEMBL15350476 | 0.85 | AAK1 (0.40) | AAK1IDH1 | |
| Hydrochloric Acid SCHEMBL2717390 | 0.84 | MAPK1 (0.41) | SCN9AMAPK1AAK1 | |
| SCHEMBL18266454 | 0.80 | SCN9A (0.34) | SCN9AAAK1 | |
| SCHEMBL4550399 | 0.80 | SCN9A (0.39) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520296-B | Pyrrolopyridinone derivatives as TTX-S blocker | 拉夸里亚创药株式会社 | 2016-11-16 | — | — | CN | disclosed |