Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 4/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10324235 | 0.90 | SSTR4 (0.46) | SSTR4NFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL16174985 | 0.86 | SSTR4 (0.42) | SSTR4HDAC1HDAC6HDAC5KMT2A | |
| SCHEMBL16239660 | 0.83 | SSTR4 (0.41) | SSTR4NFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL24599918 | 0.80 | SSTR4 (0.39) | SSTR4NFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL364602 | 0.80 | SSTR4 (0.39) | SSTR4HDAC1HDAC6HDAC5KMT2A | |
| SCHEMBL24599912 | 0.79 | SSTR4 (0.39) | SSTR4NFE2L2HDAC1HDAC6HDAC5 | |
| SCHEMBL24599915 | 0.78 | SSTR4 (0.38) | SSTR4HDAC1HDAC6HDAC5ALDH1A1 | |
| SCHEMBL24599913 | 0.78 | SSTR4 (0.38) | SSTR4HDAC1HDAC6HDAC5ALDH1A1 | |
| SCHEMBL24599855 | 0.78 | SSTR4 (0.38) | SSTR4HDAC1HDAC6HDAC5ALDH1A1 | |
| SCHEMBL16175292 | 0.76 | EPHX2 (0.39) | SSTR4HDAC1HDAC6HDAC5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104520296-B | Pyrrolopyridinone derivatives as TTX-S blocker | 拉夸里亚创药株式会社 | 2016-11-16 | — | — | CN | disclosed |