SCHEMBL28081114

CC(C)CC(NC(=O)C(C)NC(=O)C(NC(=O)C(NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(N)CCC(=O)O)C(C)C)C(C)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	9/20	0.59

▸	NPBWR1	P48145	2/20	0.57

▸	NR3C1	P04150	3/20	0.56

▸	RXFP1	Q9HBX9	3/20	0.56

▸	ECE1	P42892	1/20	0.55

▸	MUS81	Q96NY9	1/20	0.55

▸	IL23R	Q5VWK5	2/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28081133	0.95	GLP1R (0.61)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL28081219	0.95	GLP1R (0.61)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL28081223	0.94	ERAP2 (0.58)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL28081239	0.93	GLP1R (0.64)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL28081101	0.93	GLP1R (0.58)	GLP1RNPBWR1NR3C1ECE1MUS81
SCHEMBL30403458	0.91	GLP1R (0.61)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL29429569	0.90	GLP1R (0.61)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL29583767	0.90	CXCR4 (0.61)	GLP1RNPBWR1NR3C1RXFP1ECE1
SCHEMBL30204843	0.89	GLP1R (0.55)	GLP1RIL23R
SCHEMBL29736308	0.88	ERBB2 (0.62)	GLP1RNPBWR1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-105683390-A	HbA1c measurement method using amadoriase acting on glycated peptides	龟甲万株式会社	2016-06-15	—	—	CN	claimed
CN-105683390-A	HbA1c measurement method using amadoriase acting on glycated peptides	龟甲万株式会社	2016-06-15	—	—	CN	disclosed