Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76764 | 0.98 | NPC1 (0.47) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Fluoride SCHEMBL30330669 | 0.96 | NPC1 (0.46) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28350131 | 0.96 | NPC1 (0.46) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Cyanide SCHEMBL30330916 | 0.92 | NPC1 (0.43) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| SCHEMBL27926693 | 0.90 | NPC1 (0.56) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| SCHEMBL28249044 | 0.90 | NPC1 (0.56) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30330224 | 0.88 | NPC1 (0.55) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30330486 | 0.88 | NPC1 (0.55) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Fluoride SCHEMBL30330170 | 0.88 | NPC1 (0.55) | NPC1RAB9AHTTLMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30330954 | 0.88 | NPC1 (0.55) | NPC1RAB9AHTTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756687-A | Method for synthesizing dialkyl dithiocarbamic acid ester by adopting pyrrole alkaline ionic liquid as catalyst | 江苏飞亚化学工业集团股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-9163166-B2 | Adhesive composition, optical member, and surface protective sheet | CHEIL INDUSTRIES, INC. (KR) | 2015-10-20 | — | — | US | disclosed |
| US-20150111033-A1 | ADHESIVE COMPOSITION, OPTICAL MEMBER, AND SURFACE PROTECTIVE SHEET | SONG CHEONG HUN (KR) | 2015-04-23 | — | — | US | disclosed |
| EP-2215173-B1 | ADHESIVE COMPOSITION, AND OPTICAL MEMBER, SURFACE PROTECTIVE SHEET | CHEIL IND INC (KR) | 2014-05-14 | — | — | EP | disclosed |
| US-20100239859-A1 | Adhesive composition, optical member, and surface protective sheet | Wuxi Hengxin Optoelectronic Materials Co., Ltd. (CN) | 2010-09-23 | — | — | US | disclosed |