SCHEMBL2808200

SCHEMBL2808200

CCc1ccc(NC2CC(C)N(C(C)=O)c3ccc(C)cc32)cc1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 6/20 0.64
BRD2 P25440 6/20 0.64
BRD3 Q15059 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17517792 0.92 BRD4 (0.64) BRD4BRD2BRD3
SCHEMBL5837342 0.92 BRD4 (0.64) BRD4BRD2BRD3
SCHEMBL5837340 0.92 BRD4 (0.64) BRD4BRD2BRD3
SCHEMBL224018 0.91 BRD4 (0.74) BRD4BRD2BRD3
SCHEMBL5836515 0.91 BRD4 (0.74) BRD4BRD2BRD3
SCHEMBL17503199 0.91 BRD4 (0.74) BRD4BRD2BRD3
SCHEMBL17503200 0.91 BRD4 (0.74) BRD4BRD2BRD3
SCHEMBL17503201 0.91 BRD4 (0.74) BRD4BRD2BRD3
SCHEMBL13178434 0.88 BRD4 (0.65) BRD4BRD2BRD3
SCHEMBL2741201 0.88 BRD4 (0.58) BRD4BRD2BRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004197-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT KOWA COMPANY, LTD. (JP) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004197-A1 PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR ANEMIA COMPRISING TETRAHYDROQUINOLINE COMPOUND AS ACTIVE INGREDIENT EPOR, HBG1, HBG2 BRD4 861/4885BRD2 1499/4885BRD3 1556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.