SCHEMBL28083103

SCHEMBL28083103

Brc1ccnc2c(Br)ccnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
HSP90AA1 P07900 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TP53 P04637 2/20 0.41
HTT P42858 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
USP2 O75604 1/20 0.41
PRKCI P41743 1/20 0.41
MAPK1 P28482 1/20 0.39
DAO P14920 1/20 0.38
CCR1 P32246 3/20 0.38
CCR5 P51681 3/20 0.38
CCR8 P51685 3/20 0.38
MAPT P10636 2/20 0.37
ALDH1A1 P00352 2/20 0.37
APAF1 O14727 1/20 0.37
TDP2 O95551 1/20 0.37
CASP3 P42574 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30439125 0.87 MAPK1 (0.44) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL1126077 0.87 MAPK1 (0.44) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL25324632 0.84 CCR1 (0.50) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL30509484 0.84 CCR1 (0.50) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL20699181 0.83 MAPK1 (0.38) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL2206337 0.79 CCR1 (0.50) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL1426892 0.77 KDM4E (0.46) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
Bromide SCHEMBL20571658 0.75 KDM4E (0.44) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL21800374 0.73 MAPK1 (0.35) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A
SCHEMBL18980173 0.73 CCR1 (0.39) KDM4ESMN1; SMN2HSP90AA1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213409-A Material for organic electroluminescent element, and consumer product 上海八亿时空先进材料有限公司 2022-03-22 CN disclosed
CN-106083845-A A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application 金陵科技学院 2016-11-09 CN disclosed