Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.78 |
| ▸ | CASP1 | P29466 | 7/20 | 0.54 |
| ▸ | CASP5 | P51878 | 7/20 | 0.54 |
| ▸ | CASP4 | P49662 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2807024 | 0.99 | PPARG (0.79) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2807168 | 0.97 | PPARG (0.83) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2804707 | 0.93 | PPARG (0.78) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2808295 | 0.92 | PPARG (0.76) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2804581 | 0.92 | PPARG (0.76) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2805018 | 0.88 | PPARG (0.83) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2807357 | 0.88 | PPARG (0.83) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2812228 | 0.88 | PPARG (1.00) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2805810 | 0.88 | PPARG (1.00) | PPARGCASP1CASP5CASP4PPARA | |
| SCHEMBL2809044 | 0.88 | PPARG (1.00) | PPARGCASP1CASP5CASP4PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513233-B2 | Pyrimidinyl-propionic acid derivatives and their use as PPAR agonists | SHANGHAI INSTITUTE OF MATERIA MEDICA, CAS (CN) | 2013-08-20 | — | — | US | disclosed |
| US-8513233-B2 | Pyrimidinyl-propionic acid derivatives and their use as PPAR agonists | SHANGHAI INSTITUTE OF MATERIA MEDICA, CAS (CN) | 2013-08-20 | — | — | US | disclosed |
| US-8513233-B2 | Pyrimidinyl-propionic acid derivatives and their use as PPAR agonists | SHANGHAI INSTITUTE OF MATERIA MEDICA, CAS (CN) | 2013-08-20 | — | — | US | disclosed |
| US-20100240636-A1 | PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | SHENYANG SUNSHINE PHARMACEUTICAL COMPANY LIMITED (CN) | 2010-09-23 | — | — | US | disclosed |
| US-20100240636-A1 | PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | SHENYANG SUNSHINE PHARMACEUTICAL COMPANY LIMITED (CN) | 2010-09-23 | — | — | US | disclosed |
| US-20100240636-A1 | PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | SHENYANG SUNSHINE PHARMACEUTICAL COMPANY LIMITED (CN) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240636-A1 | PYRIMIDINYL-PROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS | PPARA, PPARD, PPARG | PPARG 3/4885CASP1 2838/4885CASP5 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.