Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.45 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.45 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphorylethanolamine SCHEMBL27676040 | 1.00 | LPAR3 (0.46) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Phosphorylethanolamine SCHEMBL28083434 | 0.94 | S1PR1 (0.55) | LPAR3LPAR1ENPP2LPAR2LPAR6 | |
| Phosphocholine SCHEMBL28083493 | 0.87 | FABP3 (0.53) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Phosphocholine SCHEMBL27650430 | 0.87 | FABP3 (0.53) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Phosphocholine SCHEMBL8790092 | 0.87 | FABP3 (0.53) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Phosphoric Acid SCHEMBL28324932 | 0.87 | MAPT (0.54) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Phosphoric Acid SCHEMBL7807542 | 0.87 | MAPT (0.54) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Pyrophosphoric Acid SCHEMBL8723090 | 0.86 | MAPT (0.50) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Pyrophosphoric Acid SCHEMBL5918479 | 0.86 | MAPT (0.50) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 | |
| Pyrophosphoric Acid SCHEMBL1664878 | 0.86 | MAPT (0.50) | LPAR3LPAR1ENPP2SMN1; SMN2LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717205-B | Treatment of cancers and metastases with suspensions of cilengitide in carrier | 默克专利股份公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-102652015-B | Pharmaceutical composition comprising oligopeptides, preferably cilengitide | 默克专利有限公司 | 2016-08-03 | — | — | CN | disclosed |