Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | FGR | P09769 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651427 | 0.85 | HSD17B10 (0.54) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL38925 | 0.85 | HSD17B10 (0.54) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL9550986 | 0.85 | HSD17B10 (0.54) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL1727316 | 0.83 | HSD17B10 (0.58) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL18241644 | 0.83 | HSD17B10 (0.58) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27625138 | 0.83 | HSD17B10 (0.52) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL8677116 | 0.82 | MAOB (0.45) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL4229766 | 0.82 | CA12 (0.41) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL6130217 | 0.82 | HSD17B10 (0.42) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 | |
| SCHEMBL9217300 | 0.82 | HSD17B10 (0.74) | HSD17B10CYP3A4TDP1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068878-B | There is the polymer of carbazole structure unit | 默克专利有限公司 | 2016-07-20 | — | — | CN | disclosed |