1,3,5-Trichlorobenzene

1,3,5-Trichlorobenzene

SCHEMBL28084249

Clc1cc(Cl)cc(Cl)c1.O=COC=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.50
ERN1 O75460 4/20 0.40
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
TPMT P51580 1/20 0.38
IDO1 P14902 2/20 0.35
AHR P35869 2/20 0.35
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3,5-Trichlorobenzene SCHEMBL27517784 0.76 TSHR (0.61) TSHRERN1TP53CYP3A4TPMT
SCHEMBL2088497 0.75 TSHR (0.42) TSHRERN1TP53CYP3A4TPMT
1,3,5-Trichlorobenzene SCHEMBL27851071 0.73 TSHR (0.57) TSHRERN1TP53CYP3A4TPMT
1,3,5-Trichlorobenzene SCHEMBL27911704 0.73 TSHR (0.57) TSHRERN1TP53CYP3A4TPMT
1,3,5-Trichlorobenzene SCHEMBL28193463 0.71 TSHR (0.53) TSHRERN1TP53CYP3A4TPMT
SCHEMBL15547958 0.71 TDP1 (0.31) ALDH1A1TDP1
1,3,5-Trichlorobenzene SCHEMBL429512 0.71
SCHEMBL6244 0.71
SCHEMBL15547959 0.71 TDP1 (0.31) ALDH1A1TDP1
SCHEMBL5545007 0.69 IDO1 (0.41) TSHRERN1TPMTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103781764-B Method for producing pest control agent 明治制果药业株式会社 2016-07-20 CN claimed