Phosphine

Phosphine

SCHEMBL28084508

O=C(Oc1ccccc1)c1ccccc1C(=O)Oc1ccccc1.P

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.73
HPGD P15428 1/20 0.73
ALOX15 P16050 1/20 0.73
MAPT P10636 4/20 0.68
KDM4E B2RXH2 3/20 0.68
TDP1 Q9NUW8 2/20 0.68
ALDH1A1 P00352 5/20 0.56
LMNA P02545 2/20 0.55
NR4A2 P43354 1/20 0.55
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
ADORA3 P0DMS8 1/20 0.55
CHRM1 P11229 1/20 0.55
TBXA2R P21731 1/20 0.55
SLC6A2 P23975 1/20 0.55
PDE4A P27815 1/20 0.55
ADRA1A P35348 1/20 0.55
KDR P35968 1/20 0.55
SLC6A3 Q01959 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29437924 0.98 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL69868 0.98 HSD17B10 (0.76) HSD17B10HPGDALOX15MAPTKDM4E
Hydrazine SCHEMBL28313769 0.96 HSD17B10 (0.68) HSD17B10HPGDALOX15MAPTKDM4E
Bicarbonate SCHEMBL27452806 0.95 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Methane SCHEMBL27316738 0.95 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
Hydrogen Sulfide SCHEMBL28157119 0.95 HSD17B10 (0.73) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL27566769 0.93 HSD17B10 (0.70) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL30778294 0.91 HSD17B10 (0.68) HSD17B10HPGDALOX15MAPTKDM4E
SCHEMBL251479 0.91 HSD17B10 (0.68) HSD17B10HPGDALOX15MAPTKDM4E
Phthalic Acid SCHEMBL9391164 0.91 HSD17B10 (0.68) HSD17B10HPGDALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106939075-B A kind of hydrophilic polyester and its block copolymer 银谷制药有限责任公司 2019-09-17 CN claimed
CN-105924942-A High-strength and high-flame retardation polyurethane composite heat insulation plate 安徽广燕新材料科技有限责任公司 2016-09-07 CN claimed
CN-105849108-A Preparation method of phosphatidylinositol 3-kinase inhibitor 吉利德卡利斯托加公司 2016-08-10 CN claimed
CN-110229190-A A kind of fire retardant of the P elements containing multivalent state and preparation method thereof 中国科学技术大学 2019-09-13 CN disclosed
CN-105637013-B The method for preparing polyether carbonate polyol 科思创德国股份有限公司 2019-07-30 CN disclosed
CN-110072949-A Weatherability enhancer, the coating resin combination of metal nanometer line layer and laminated body containing metal nanometer line 星光PMC株式会社 2019-07-30 CN disclosed
CN-110036087-A REFRIGERANT, HEAT TRANSFER COMPOSITIONS, METHODS, AND SYSTEMS 霍尼韦尔国际公司 2019-07-19 CN disclosed
CN-104662687-B Salts of phosphorus oxide for use as n-type dopants in organic electronic devices 西门子公司 2019-06-14 CN disclosed
CN-109791224-A Optics polyester film and transparent and electrically conductive film 三菱瓦斯化学株式会社 2019-05-21 CN disclosed
CN-109715613-A Heterocyclic compound 武田药品工业株式会社 2019-05-03 CN disclosed
CN-109575253-A A kind of preparation method of PTT base low-melting copolyesters 中原工学院 2019-04-05 CN disclosed
CN-105579475-B Low vinyl bond modified elastomeric copolymers 盛禧奥欧洲有限责任公司 2018-11-02 CN disclosed
CN-106366105-B Preparation method and application of difluoroallyl borate 大连理工大学 2018-03-13 CN disclosed
CN-107629183-A Modified resin and resin combination 旭化成株式会社 2018-01-26 CN disclosed
CN-104870193-B (ethene, vinyl acetal) copolymer and their purposes in Lighographic printing plate precursor 爱克发印艺公司 2017-12-22 CN disclosed
CN-104987350-B One kind has chiral alpha aminophosphonate compound and preparation and the application of the heterocycle containing benzothiazole of antiviral activity 贵州大学 2017-12-05 CN disclosed
CN-106796398-A Lighographic printing plate precursor comprising (Ethylene vinyl acetal) copolymer 爱克发印艺公司 2017-05-31 CN disclosed
CN-106147066-A A kind of high-performance modified pvc material 安徽瑞鑫自动化仪表有限公司 2016-11-23 CN disclosed
CN-105924943-A High-flame retardation polyurethane composite heat insulation plate 安徽广燕新材料科技有限责任公司 2016-09-07 CN disclosed
CN-103694378-B A kind of method of synthetic solvent type rare-earth rubber catalyst 华宇橡胶有限责任公司 2016-08-31 CN disclosed