SCHEMBL28084646

SCHEMBL28084646

CCOc1c(C)cccc1COC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 8/20 0.38
SCN8A Q9UQD0 3/20 0.38
LMNA P02545 2/20 0.38
SCN1A P35498 2/20 0.38
SCN5A Q14524 2/20 0.38
SCN9A Q15858 2/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38
NFKB1 P19838 2/20 0.38
CYP2C9 P11712 1/20 0.38
TSHR P16473 1/20 0.38
KCNK3 O14649 1/20 0.38
CACNA1F O60840 1/20 0.38
KCNK2 O95069 1/20 0.38
GBA1 P04062 1/20 0.38
MAOA P21397 1/20 0.38
HTR2A P28223 1/20 0.38
SLC6A4 P31645 1/20 0.38
HTR2B P41595 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30572074 1.00 SCN4A (0.38) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL7803355 0.82 SCN4A (0.37) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL16954557 0.82 MAPT (0.44) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL147753 0.80 SCN4A (0.54) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL4109060 0.79 SCN8A (0.44) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL16961333 0.79 PTGER4 (0.41) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL11129043 0.79 SCN4A (0.39) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL9653476 0.79 CYP4F2 (0.41) SCN4ASCN8ALMNASCN1ASCN5A
SCHEMBL5572974 0.76 ABCB1 (0.48) LMNATSHRHTR1AADRA1DADRA1A
SCHEMBL1251942 0.76 TAAR1 (0.55) SCN4ASCN8ALMNASCN1ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105829050-A Improvements in or relating to foam filled honeycomb structures 泽费罗斯股份有限公司 2016-08-03 CN disclosed