Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LIG1 | P18858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217447 | 1.00 | SLC6A2 (0.38) | SLC6A2SLC6A3LMNACYP2A6HTR3A | |
| SCHEMBL28949260 | 1.00 | SLC6A2 (0.38) | SLC6A2SLC6A3LMNACYP2A6HTR3A | |
| SCHEMBL14654378 | 0.80 | HPGD (0.46) | LMNARAB9AALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23447069 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL8287019 | 0.79 | ESR2 (0.36) | LMNARAB9AALDH1A1HSD17B10 | |
| SCHEMBL16705503 | 0.79 | — | — | |
| SCHEMBL23161981 | 0.79 | MEN1 (0.33) | — | |
| SCHEMBL13821980 | 0.79 | MAPT (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL22908940 | 0.79 | — | — | |
| SCHEMBL12993026 | 0.79 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323599-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115667250-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-105837564-B | One kind benzothiazepines containing pyridine derivative, preparation method and the usage | 贵州大学 | 2019-02-05 | — | — | CN | disclosed |
| CN-105837564-A | Pyridine-containing benzothiazepine derivatives, and preparation method and application thereof | 贵州大学 | 2016-08-10 | — | — | CN | disclosed |
| CN-104710360-A | Synthesis method of benzo[f]quinoline derivatives | UNIV TIANJIN POLYTECHNIC | 2015-06-17 | — | — | CN | disclosed |
| CN-104710361-A | Benzo[f]quinoline derivatives catalyzed and synthesized by multiple catalysts | UNIV TIANJIN POLYTECHNIC | 2015-06-17 | — | — | CN | disclosed |