Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 19/20 | 0.86 |
| ▸ | MAOB | P27338 | 4/20 | 0.86 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | HTR2A | P28223 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.59 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084668 | 1.00 | KDM1A (0.86) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15411743 | 0.92 | KDM1A (1.00) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL21101609 | 0.92 | KDM1A (1.00) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15424987 | 0.92 | KDM1A (1.00) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL19513651 | 0.92 | KDM1A (1.00) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15411742 | 0.92 | KDM1A (1.00) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15424884 | 0.87 | KDM1A (0.84) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL12821568 | 0.87 | KDM1A (0.84) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL12821569 | 0.87 | KDM1A (0.84) | KDM1AMAOBDRD2HTR2ASLC6A4 | |
| SCHEMBL15425013 | 0.86 | KDM1A (0.92) | KDM1AMAOBDRD2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103857393-B | Cyclopropylamine is as LSD1 inhibitor | 葛兰素史密斯克莱知识产权（第2 号）有限公司 | 2016-08-17 | — | — | CN | disclosed |