Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | FAP | Q12884 | 6/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161732 | 0.94 | KDM4E (0.42) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL18747668 | 0.94 | KDM4E (0.42) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL18747671 | 0.94 | KDM4E (0.42) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL18747649 | 0.94 | KDM4E (0.42) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL18747702 | 0.94 | KDM4E (0.42) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL28265984 | 0.92 | KDM4E (0.41) | KDM4ECXCR4TAAR1CA1CA12 | |
| Hydrochloric Acid SCHEMBL31674975 | 0.92 | KDM4E (0.41) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL18747676 | 0.92 | KDM4E (0.39) | DPP4FAPDPP7KDM4ECXCR4 | |
| Water SCHEMBL28173239 | 0.91 | CA12 (0.39) | KDM4ECXCR4TAAR1CA1CA12 | |
| SCHEMBL18747653 | 0.88 | S1PR4 (0.36) | DPP4FAPDPP7KDM4ECXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105960249-A | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives | 赛诺菲 | 2016-09-21 | — | — | CN | disclosed |
| CN-105899191-A | Stabilized glycerol-free pharmaceutical formulations of insulin analogues and/or insulin derivatives | 赛诺菲 | 2016-08-24 | — | — | CN | disclosed |
| CN-105899190-A | Stabilized pharmaceutical formulations of insulin aspart | 赛诺菲 | 2016-08-24 | — | — | CN | disclosed |